WHO's response to the global mpox outbreak

Overview

This report provides a consolidated update on WHO’s response to mpox during the PHEIC period (August 2024–September 2025), aligned with the objectives of the extended Global strategic preparedness and response plan (SPRP). It outlines key actions taken to detect and reduce transmission, protect vulnerable populations, and strengthen readiness and response capacities across regions.

The report highlights WHO’s role across all elements of an effective health emergency response – implementation, operational support, evidence generation, coordination, and planning – while underscoring the importance of solidarity and partnership. Contributions from donors were essential in enabling WHO and partners to support countries in implementing their national mpox response plans and advancing efforts to end the outbreak.